Proton pump inhibitors, or PPIs, have been linked to severe kidney problems. These include kidney...READ MORE
First Proton Pump Inhibitor Kidney Failure Case Reaches Illinois Court
The first lawsuit alleging that the use of Nexium, a proton pump inhibitor, led to kidney failure has been filed in the U.S. District Court, Southern District of Illinois.
A Devastating Diagnosis
A kidney transplant patient filed the lawsuit, claiming that he developed renal failure after using the medication. Nexium and other proton pump inhibitors (PPIs) are commonly used to treat heartburn, peptic ulcer disease and other disorders.
Other drugs in the PPI class include:
Nexium, Prilosec and Zegerid are available both over the counter and through a prescription.
After he began taking Nexium in 2006, the plaintiff alleges, he developed chronic kidney disease that eventually turned into kidney failure. As a result, he had to undergo a kidney transplant.
The plaintiff alleges that the maker of Nexium, AstraZeneca, was fully aware that the drug could cause kidney damage, yet continued to market Nexium aggressively. He also claims that had he received the proper warnings regarding risks of kidney problems, he may have been able to avoid his injuries.
In April, the Journal of the American Society of Nephrology published a study that suggested the use of PPIs could increase the risk of renal failure by 96 percent, and could increase the risk for chronic kidney disease by 28 percent when compared to another type of heartburn medication known as an H2-blocker. JAMA (the Journal of the American Medical Association) published a study in January showing that PPIs could increase the risk of chronic kidney disease by up to 50 percent.